Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate

Wei Dai; Amy Peterson; Thomas Kenney; Haley Burrous; Denise J. Montell

doi:10.1038/s41467-017-01322-9

Nature Communications (Nov 2017)

Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate

Wei Dai,
Amy Peterson,
Thomas Kenney,
Haley Burrous,
Denise J. Montell

Affiliations

Wei Dai: MCDB Department, University of California
Amy Peterson: MCDB Department, University of California
Thomas Kenney: MCDB Department, University of California
Haley Burrous: MCDB Department, University of California
Denise J. Montell: MCDB Department, University of California

DOI: https://doi.org/10.1038/s41467-017-01322-9
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 14

Abstract

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In the Drosophila ovary, it is unclear how signalling from the stem cell niche regulates follicle precursor cell fate/differentiation. Here, the authors use quantitative microscopy to define the role of Wnt, Hedgehog and Notch signalling in progenitor cells, showing regulation of cell fate and differentiation.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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