Frontiers in Pediatrics (Nov 2014)

Hypoplastic left heart syndrome – Unresolved Issues

  • Raoul Roman Arnold,
  • Tsvetomir eLoukanov,
  • Matthias eGorenflo

DOI
https://doi.org/10.3389/fped.2014.00125
Journal volume & issue
Vol. 2

Abstract

Read online

Hypoplastic left heart syndrome (HLHS) is one of the most challenging congenital heart defects. At present it is expected that - at best - 70% of newborns with HLHA will reach adulthood. This review addresses the problems of right ventricular failure and insufficient growth of pulmonary vasculature in these patients. In order to further improve long-term prognosis translational research to control right ventricular function and growth of pulmonary arteries and progress in chronic circulatory support are clearly needed to provide a further improvement for adults with HLHS.

Keywords