Phytochemical study of Illicium angustisepalum and its biological activities

Karina M. Szymulanska-Ramamurthy; Ming Zhao; Chun-Tao Che

doi:10.1016/j.apsb.2017.06.002

Acta Pharmaceutica Sinica B (Jul 2017)

Phytochemical study of Illicium angustisepalum and its biological activities

Karina M. Szymulanska-Ramamurthy,
Ming Zhao,
Chun-Tao Che

Affiliations

Karina M. Szymulanska-Ramamurthy: Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago 60612, USA
Ming Zhao: Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago 60612, USA
Chun-Tao Che: Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago 60612, USA

DOI: https://doi.org/10.1016/j.apsb.2017.06.002
Journal volume & issue: Vol. 7, no. 4
pp. 485 – 490

Abstract

Read online

Sixteen compounds, including two new natural products (1 and 2), were obtained from the twigs of Illicium angustisepalum. The structures were elucidated based on NMR, MS, IR data and optical rotation values. Compounds 4, 5, 6 and 8 displayed moderate antibacterial activities against clinical isolates; compounds 4, 5, 8, 9 and 15 protected neural cells against oxidative stress; and compounds 10 and 14 exhibited anti-acetylcholinesterase activity.

Published in Acta Pharmaceutica Sinica B

ISSN: 2211-3835 (Print); 2211-3843 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: https://www.sciencedirect.com/journal/acta-pharmaceutica-sinica-b

About the journal

Abstract

Keywords