Nature Communications (Apr 2020)
LipidCreator workbench to probe the lipidomic landscape
- Bing Peng,
- Dominik Kopczynski,
- Brian S. Pratt,
- Christer S. Ejsing,
- Bo Burla,
- Martin Hermansson,
- Peter Imre Benke,
- Sock Hwee Tan,
- Mark Y. Chan,
- Federico Torta,
- Dominik Schwudke,
- Sven W. Meckelmann,
- Cristina Coman,
- Oliver J. Schmitz,
- Brendan MacLean,
- Mailin-Christin Manke,
- Oliver Borst,
- Markus R. Wenk,
- Nils Hoffmann,
- Robert Ahrends
Affiliations
- Bing Peng
- Leibniz-Institut für Analytische Wissenschaften – ISAS - e.V.
- Dominik Kopczynski
- Leibniz-Institut für Analytische Wissenschaften – ISAS - e.V.
- Brian S. Pratt
- University of Washington, Department of Genome Sciences
- Christer S. Ejsing
- Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK-
- Bo Burla
- Singapore Lipidomics Incubator (SLING), Life Sciences Institute, National University of Singapore
- Martin Hermansson
- Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK-
- Peter Imre Benke
- Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore
- Sock Hwee Tan
- Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital
- Mark Y. Chan
- Department of Medicine, Yong Loo Lin School of Medicine, National University Hospital
- Federico Torta
- Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore
- Dominik Schwudke
- Research Center Borstel, Leibniz Lung Center
- Sven W. Meckelmann
- Applied Analytical Chemistry, University of Duisburg-Essen
- Cristina Coman
- Leibniz-Institut für Analytische Wissenschaften – ISAS - e.V.
- Oliver J. Schmitz
- Applied Analytical Chemistry, University of Duisburg-Essen
- Brendan MacLean
- University of Washington, Department of Genome Sciences
- Mailin-Christin Manke
- Department of Cardiology and Cardiovascular Medicine, University of Tübingen
- Oliver Borst
- Department of Cardiology and Cardiovascular Medicine, University of Tübingen
- Markus R. Wenk
- Singapore Lipidomics Incubator (SLING), Life Sciences Institute, National University of Singapore
- Nils Hoffmann
- Leibniz-Institut für Analytische Wissenschaften – ISAS - e.V.
- Robert Ahrends
- Leibniz-Institut für Analytische Wissenschaften – ISAS - e.V.
- DOI
- https://doi.org/10.1038/s41467-020-15960-z
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 14
Abstract
Targeted mass spectrometry enables reproducible and accurate lipid quantification but dedicated software tools to develop targeted lipidomics assays are lacking. Here, the authors develop a targeted lipidomics workbench and lipid knowledgebase for the streamlined generation of targeted assays.
