Catheter-related bloodstream infection due to biofilm-producing Capnocytophaga sputigena
Shelcie Fabre,
Yesha Malik,
Adriana van De Guchte,
Lourdes A. Delgado-Noguera,
Melissa R. Gitman,
Michael D. Nowak,
Emilia M. Sordillo,
Matthew M. Hernandez,
Alberto E. Paniz-Mondolfi
Affiliations
Shelcie Fabre
Clinical Microbiology Laboratory, Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
Yesha Malik
Department of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
Adriana van De Guchte
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
Lourdes A. Delgado-Noguera
Infectious Diseases Division, Venezuelan Research Incubator and the Zoonosis and Emerging Pathogens Regional Collaborative Network, Barquisimeto, Lara, 3001, Venezuela; Instituto de Investigaciones Biomédicas IDB, Barquisimeto, Lara, 3001, Venezuela; Health Sciences Department, College of Medicine, Universidad Centroccidental Lisandro Alvarado, Barquisimeto, Lara, 3001, Venezuela
Melissa R. Gitman
Clinical Microbiology Laboratory, Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
Michael D. Nowak
Clinical Microbiology Laboratory, Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
Emilia M. Sordillo
Clinical Microbiology Laboratory, Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
Matthew M. Hernandez
Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
Alberto E. Paniz-Mondolfi
Clinical Microbiology Laboratory, Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA; Corresponding author at: Clinical Microbiology Laboratory, Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Capnocytophaga sputigena is a facultatively-anaerobic bacterium that is part of the human oropharyngeal microflora. Although C. sputigena bacteremia is uncommon, systemic infections have been reported in both immunocompetent and immunocompromised patients. We report a case of catheter-related bloodstream infection by C. sputigena and highlight its enhanced biofilm-forming capacity in vitro.
