Nature Communications (Dec 2018)

Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy

  • Inka Negwer,
  • Andreas Best,
  • Meike Schinnerer,
  • Olga Schäfer,
  • Leon Capeloa,
  • Manfred Wagner,
  • Manfred Schmidt,
  • Volker Mailänder,
  • Mark Helm,
  • Matthias Barz,
  • Hans-Jürgen Butt,
  • Kaloian Koynov

DOI
https://doi.org/10.1038/s41467-018-07755-0
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 9

Abstract

Read online

While nanocarrier-based drug delivery is a promising therapeutic approach, in situ characterization of drug nanocarriers in blood remains difficult. Here, the authors demonstrate how the fluorescence correlation spectroscopy can be used to directly characterize drug nanocarriers in flowing blood.