Nature Communications (May 2022)

On the origins of conductive pulse sensing inside a nanopore

  • Lauren S. Lastra,
  • Y. M. Nuwan D. Y. Bandara,
  • Michelle Nguyen,
  • Nasim Farajpour,
  • Kevin J. Freedman

DOI
https://doi.org/10.1038/s41467-022-29758-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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Conductive events during nanopore sensing, are seen typically under low salt conditions and widely thought to arise from counterions brought into the pore via analyte. Here, authors show that an imbalance of ionic fluxes lead to conductive events.