Arquivos Brasileiros de Cardiologia (Jan 2005)

Síndromes coronarianas agudas na ausência de doença arterial coronariana significativa Acute coronary syndromes in the absence of significant coronary artery disease

  • Maria das Graças Viana Pinheiro,
  • Alvaro Rabelo Jr.,
  • Rogerio Santos de Jesus,
  • Luciana Cunha Nascimento,
  • Ursula Maria Moreira Costa

DOI
https://doi.org/10.1590/S0066-782X2005000100006
Journal volume & issue
Vol. 84, no. 1
pp. 24 – 28

Abstract

Read online

OBJETIVO: Avaliar as características clínicas, a evolução e as complicações intra-hospitalares de pacientes com síndromes coronarianas agudas (SCA) na ausência de doença arterial coronariana (DAC) obstrutiva significativa. MÉTODOS: Estudo transversal envolvendo pacientes internados, de agosto/96 a março/02, com síndromes coronarianas agudas, com e sem supradesnivelamento ST, analisando as características clinicas, demográficas e complicações intra-hospitalares nos casos com (>50%) e sem (OBJECTIVE: To assess the clinical characteristics, evolution, and in-hospital complications of patients with acute coronary syndromes (ACS) in the absence of significant obstructive coronary artery disease (CAD). METHODS: Cross-sectional study of patients hospitalized from August 1996 to March 2002 with acute coronary syndrome, with or without an elevation in the ST segment, and with (= 50%) or without (<50%) significant coronary stenosis. Their clinical and demographic characteristics and their in-hospital complications were analyzed. RESULTS: Of the 1351 patients admitted with acute coronary syndrome, 28% had an elevation in the ST segment and 72% had no elevation. The patients with acute coronary syndrome with no elevation in the ST segment and no significant coronary obstruction were younger, predominantly females, and had a lower frequency of dyslipidemia, previous coronary arterial disease, diabetes mellitus, smoking, and systemic arterial hypertension, when compared with those with significant obstructive lesion. Among the individuals with acute coronary syndrome and an elevation in the ST segment, smoking was the most prevalent risk factor in patients with nonsignificant obstructive lesion. In regard to complications, recurring ischemia, congestive heart failure, and arrhythmias were more frequent in patients with acute coronary syndrome with no elevation in the ST segment and no significant obstructive coronary lesion. CONCLUSION: Patients with acute coronary syndrome with no elevation in the ST segment and with nonsignificant obstructive coronary lesions are younger, predominantly females, have a greater frequency of risk factors for coronary arterial disease, and a lower incidence of complications as compared with patients with significant obstructive coronary lesion.

Keywords