Stem Cell Research & Therapy (Jan 2025)

Mesenchymal stromal cell exosomes for drug delivery of prostate cancer treatments: a review

  • Chengran Wang,
  • Yanshuo Feng,
  • Xinao Rong,
  • Jingguo Yan,
  • Baisong Lv,
  • Hongyu Jiang,
  • Lian Duan,
  • Jinlan Jiang

DOI
https://doi.org/10.1186/s13287-025-04133-8
Journal volume & issue
Vol. 16, no. 1
pp. 1 – 20

Abstract

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Abstract Interest in prostate cancer as a research topic has gradually increased. As a result, a series of innovative treatment strategies have emerged with an in-depth understanding of the disease. Owing to their unique biological characteristics, mesenchymal stromal cell exosomes (MSC-Exos) have garnered significant attention for their potential to deliver targeted drugs and enable precise prostate cancer treatment. Herein, prostate cancer treatment with MSC-Exos drug-delivery systems is reviewed. This review provides a comprehensive introduction to the advantages of these systems, current research trends and progress, as well as an analysis of current challenges and future research directions. Moreover, this review lays a solid foundation for the continued development and application of MSC-Exos. Graphical abstract

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