Design, Characterization, and 3D Printing of Cardiovascular Stents with Zero Poisson’s Ratio in Longitudinal Deformation
Chengjin Wang,
Lei Zhang,
Yongcong Fang,
Wei Sun
Affiliations
Chengjin Wang
Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing, Beijing 100084, China; “Biomanufacturing and Engineering Living Systems” Innovation International Talents Base (111 Base), Beijing 100084, China
Lei Zhang
Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing, Beijing 100084, China; “Biomanufacturing and Engineering Living Systems” Innovation International Talents Base (111 Base), Beijing 100084, China; Corresponding author.
Yongcong Fang
Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing, Beijing 100084, China; “Biomanufacturing and Engineering Living Systems” Innovation International Talents Base (111 Base), Beijing 100084, China
Wei Sun
Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing, Beijing 100084, China; “Biomanufacturing and Engineering Living Systems” Innovation International Talents Base (111 Base), Beijing 100084, China; Department of Mechanical Engineering, Drexel University, Philadelphia, PA 19104, USA
Inherent drawbacks associated with drug-eluting stents have prompted the development of bioresorbable cardiovascular stents. Additive manufacturing (3-dimentional (3D) printing) has been widely applied in medical devices. In this study, we develop a novel screw extrusion-based 3D printing system with a new designed mini-screw extruder to fabricate stents. A stent with a zero Poisson’s ratio (ZPR) structure is designed, and a preliminary monofilament test is conducted to investigate appropriate fabrication parameters. 3D-printed stents with different geometric structures are fabricated and analyzed by observation of the surface morphology. An evaluation of the mechanical properties and a preliminary biological evaluation of 3D-printed stents with different parameters are carried out. In conclusion, the screw extrusion-based 3D printing system shows potential for customizable stent fabrication.
