Dynamics of myocardial perfusion in scar tissue according to stress CMR in patients with coronary artery disease undergoing endovascular recanalization of CTO of right coronary artery

Abstract

Objective. The aim of the study was to evaluate the perfusion of scar tissue in the concerned basin blood supply before and after PCI in the presence of CTO RCA by using CMRI with delayed contrast enhancement and pharmacological stress test.Methods. The results of prospective randomized study involving two groups of patients with the presence of СТO coronary arteries and PIC (scar) are presented. The first group was with successful PCI, the second group received only conservative therapy. Delayed contrast-enhanced CMRI with a stress test was performed in all patients at baseline and after 2 months.Results. Group 1 had a significantly reduced mean number of segments with the presence of stress perfusion defects in the scar tissue during the control cardiac MRI, from 2.84 (1.64) to 2.00 (1.61), the mean difference was –0.84, 95% CI for the difference –1.23... –0.46, р<0.01. The mean (SD) number of segments with perfusion defects remained unchanged in group 2 and amounted to 2.36 (1.61).Conclusion. According to our data, endovascular recanalization of СТO coronary arteries in patients with PIC improves perfusion in the scar area.

Keywords

• Постинфарктный кардиосклероз
• Стресс-МРТ
• Чрескожное коронарное вмешательство
• Хроническая окклюзия правой коронарной артерии