Label-Free Whole Cell Biosensing for High-Throughput Discovery of Activators and Inhibitors Targeting G Protein-Activated Inwardly Rectifying Potassium Channels

• Katrin M. Krebs,
• Eva M. Pfeil,
• Katharina Simon,
• Manuel Grundmann,
• Felix Häberlein,
• Oscar M. Bautista-Aguilera,
• Michael Gütschow,
• C. David Weaver,
• Bernd K. Fleischmann,
• Evi Kostenis

Affiliations

Katrin M. Krebs

Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany

Eva M. Pfeil

Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany

Katharina Simon

Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany

Manuel Grundmann

Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany

Felix Häberlein

Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany

Oscar M. Bautista-Aguilera

Pharmaceutical Chemistry I, Institute of Pharmacy, University of Bonn, Bonn, Germany

Michael Gütschow

Pharmaceutical Chemistry I, Institute of Pharmacy, University of Bonn, Bonn, Germany

C. David Weaver

Vanderbilt Institute of Chemical Biology, Department of Pharmacology and Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States

Bernd K. Fleischmann

Institute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, Bonn, Germany

Evi Kostenis

Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany