Nature Communications (Jun 2022)
An intein-split transactivator for intersectional neural imaging and optogenetic manipulation
- Hao-Shan Chen,
- Xiao-Long Zhang,
- Rong-Rong Yang,
- Guang-Ling Wang,
- Xin-Yue Zhu,
- Yuan-Fang Xu,
- Dan-Yang Wang,
- Na Zhang,
- Shou Qiu,
- Li-Jie Zhan,
- Zhi-Ming Shen,
- Xiao-Hong Xu,
- Gang Long,
- Chun Xu
Affiliations
- Hao-Shan Chen
- Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
- Xiao-Long Zhang
- University of the Chinese Academy of Sciences
- Rong-Rong Yang
- Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
- Guang-Ling Wang
- Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
- Xin-Yue Zhu
- Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
- Yuan-Fang Xu
- Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
- Dan-Yang Wang
- Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
- Na Zhang
- Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
- Shou Qiu
- Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
- Li-Jie Zhan
- Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
- Zhi-Ming Shen
- Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
- Xiao-Hong Xu
- Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
- Gang Long
- Institut Pasteur of Shanghai, Chinese Academy of Sciences
- Chun Xu
- Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
- DOI
- https://doi.org/10.1038/s41467-022-31255-x
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 14
Abstract
Cell-type-specific recording and manipulation is important for understanding neural circuits. Here the authors describe molecular tools to access cell types based on genetics and connectivity in the brain, and demonstrated the utility of these tools in neural recording and manipulations.
