Metastatic neuroendocrine carcinoma to the mandibular gingiva from the duodenum papilla

Abstract

Neuroendocrine carcinoma is a high-grade carcinoma with morphological and immunohistochemical features of neuroendocrine differentiation. Poorly differentiated neuroendocrine carcinoma which has two subtypes (small cell or large cell type) is extremely rare, especially in head and neck cancers. Metastatic neuroendocrine carcinoma to the oral and maxillofacial region is even rarer. We report a rare case with metastatic neuroendocrine carcinoma to the mandibular gingiva from the duodenum papilla. Surgeons may consider metastatic tumors as well as primary tumors, because neuroendocrine tumors are extremely rare in oral and maxillofacial region.

Keywords

• Neuroendocrine carcinoma
• Mandible
• Duodenum papilla
• Metastatic carcinoma