Quantum hydrogen tunneling promoting halogen-atom and group transfer chemistry

Abstract

A quantum-hydrogen-tunneling-controlled halogen-atom and group transfer strategy has been successfully developed to generate carbon radicals by using the substituted cyclohexadiene as the abstractor under mild photochemical conditions, in which alkyl and aryl halides as well as numerous alcohol and thiol analogues can be activated. Mechanism investigation unveiled that this process is inhibited from thermodynamic and kinetic effects but is rendered successful through quantum tunneling.

Keywords

• Quantum hydrogen tunneling
• Halogen-atom and group transfer
• Carbon radicals
• Substituted cyclohexadiene
• Photocatalysis