A calculation-experimental study of durability of titanium booster drum of gas turbine engine (GTE) was carried out. A methodology of experimental estimation of titanium component life of GTE using structurally similar elements (SSE) has been proposed. A series of three-dimensional calculations by the finite element method of SSE cut out of the finished part was carried out to estimate the strength of the booster drum. A methodology for testing the durability of SSE in the low-cycle fatigue (LCF) area was developed, and statistical processing of the test results was performed. Tests of SSE allowed carrying out advanced-edge assessment of the durability of a full-size drum, taking into account the manufacturing technology.