Certain aspects of the systemic etiopathogenesis of dystrophic-inflammatory periodontal diseases (a literature review)

Abstract

Aim. To study the main pathogenetic mechanisms in the development of dystrophic-inflammatory periodontal diseases by analyzing scientific research results covered in current specialized literature. Material and methods. Searching, systematization, processing and analysis of scientific sources, which present modern theories of pathogenesis and development of dystrophic-inflammatory periodontal diseases. Results. The conducted data analysis from modern literary sources proves that the progression of dystrophic-inflammatory periodontal diseases depends not only on the development of local inflammation in the periodontal tissues caused by the dental plaque microflora, but also it is a reaction to the influence of systemic factors. They lead to profound changes in the body internal environment and, as a result, to structural damage of the periodontal tissues. At the same time, the results obtained do not allow the authors to clearly assess the nature of these relationships and require further in-depth studies. Conclusions. Understanding the pathogenetic mechanism of periodontal diseases allow developing optimal measures for their diagnosis, prevention and treatment.

Keywords

• periodontal disease
• pathogenesis
• generalized periodontitis
• microcirculation
• lipid peroxidation
• antioxidant protection
• immunological changes