Department of Electronic Technology, Engineering School of Bilbao, University of the Basque Country (UPV/EHU), Torres Quevedo 1, 48013 Bilbao, Spain
Igor Ayesta
Department of Applied Mathematics, Engineering School of Bilbao, University of the Basque Country (UPV/EHU), Torres Quevedo 1, 48013 Bilbao, Spain
Leire Ruiz-Rubio
Macromolecular Chemistry Research Group (LQM), Department of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Barrio Sarriena s/n, 48940 Leioa, Spain
Eneko Arrospide
Department of Applied Mathematics, Engineering School of Bilbao, University of the Basque Country (UPV/EHU), Torres Quevedo 1, 48013 Bilbao, Spain
Jose Luis Vilas-Vilela
Macromolecular Chemistry Research Group (LQM), Department of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Barrio Sarriena s/n, 48940 Leioa, Spain
Joseba Zubia
Department of Communications Engineering, Engineering School of Bilbao, University of the Basque Country (UPV/EHU), Plaza Ingeniero Torres Quevedo, 1, 48013 Bilbao, Spain
A new approach of Fiber Enhanced Raman Spectroscopy (FERS) is described within this article based on the use of Hydrogel-Core microstructured Polymer Optical Fibers (HyC-mPOF). The incorporation of the hydrogel only on the core of the Hollow-Core microstructured Polymer Optical Fiber (HC-mPOF) enables to perform FERS measurements in a functionalized matrix, enabling high selectivity Raman measurements. The hydrogel formation was continuously monitored and quantified using a Principal Component Analysis verifying the coherence between the components and the Raman spectrum of the hydrogel. The performed measurements with high and low affinity target molecules prove the feasibility of the presented HyC-mPOF platform.
