Hydrogen sulfide attenuates diabetic cardiomyopathy by inhibiting oxidative stress

Abstract

Although there are a variety of pathological mechanisms attributed to diabetic cardiomyopathy (DCM), oxidative stress is one of the most important causes of DCM. Understanding the occurrence and development of oxidative stress in DCM is very important for the new targeted therapy of DCM. In addition, hydrogen sulfide (H2S) plays an important role in the treatment of various cardiovascular diseases. In particular, H2S can reduce DCM by inhibiting oxidative stress through various pathways.

Keywords

• hydrogen sulfide (h2s)|reactive oxygen species|diabetic cardiomyopathy|protease pathway|non-protease pathway