Diagnostics (Apr 2021)

Novel App-Based Portable Spirometer for the Early Detection of COPD

  • Ching-Hsiung Lin,
  • Shih-Lung Cheng,
  • Hao-Chien Wang,
  • Wu-Huei Hsu,
  • Kang-Yun Lee,
  • Diahn-Warng Perng,
  • Hen-I. Lin,
  • Ming-Shian Lin,
  • Jong-Rung Tsai,
  • Chin-Chou Wang,
  • Sheng-Hao Lin,
  • Cheng-Yi Wang,
  • Chiung-Zuei Chen,
  • Tsung-Ming Yang,
  • Ching-Lung Liu,
  • Tsai-Yu Wang,
  • Meng-Chih Lin

DOI
https://doi.org/10.3390/diagnostics11050785
Journal volume & issue
Vol. 11, no. 5
p. 785

Abstract

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Chronic obstructive pulmonary disease (COPD) is preventable and treatable. However, many patients remain undiagnosed and untreated due to the underutilization or unavailability of spirometers. Accordingly, we used Spirobank Smart, an app-based spirometer, for facilitating the early detection of COPD in outpatient clinics. This prospective study recruited individuals who were at risk of COPD (i.e., with age of ≥40 years, ≥10 pack-years of smoking, and at least one respiratory symptoms) but had no previous COPD diagnosis. Eligible participants were examined with Spirobank Smart and then underwent confirmatory spirometry (performed using a diagnostic spirometer), regardless of their Spirobank Smart test results. COPD was defined and confirmed using the postbronchodilator forced expiratory volume in 1 s/forced vital capacity values of 1/FVC ratio of <74% that was determined using Spirobank Smart (odds ratio (OR) = 58.58, 95% CI = 27.29–125.75) and old age (OR = 3.23, 95% CI = 1.04–10.07 for 60 ≤ age < 65; OR = 5.82, 95% CI = 2.22–15.27 for age ≥ 65) had a higher risk of COPD. The Spirobank Smart is a simple and adequate tool for early COPD detection in outpatient clinics. Early diagnosis and appropriate therapy based on GOLD guidelines can positively influence respiratory symptoms and quality of life.

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