Effect of Different Anthropometric Body Indexes on Radiation Exposure in Patients Undergoing Cardiac Catheterisation and Percutaneous Coronary Intervention
Youlin Koh,
Sara Vogrin,
Samer Noaman,
Simon Lam,
Raymond Pham,
Andrew Clark,
Leah Biffin,
Laura B. Hanson,
Jason E. Bloom,
Dion Stub,
Angela L. Brennan,
Christopher Reid,
Diem T. Dinh,
Jeffrey Lefkovits,
Nicholas Cox,
William Chan
Affiliations
Youlin Koh
Department of Cardiology, Western Health, Melbourne, VIC 3021, Australia
Sara Vogrin
Centre for Epidemiology and Biostatistics, University of Melbourne, Melbourne, VIC 3010, Australia
Samer Noaman
Department of Cardiology, Western Health, Melbourne, VIC 3021, Australia
Simon Lam
Department of Radiology, Western Health, Melbourne, VIC 3021, Australia
Raymond Pham
Department of Radiology, Western Health, Melbourne, VIC 3021, Australia
Andrew Clark
Department of Radiology, Western Health, Melbourne, VIC 3021, Australia
Leah Biffin
Department of Radiology, Western Health, Melbourne, VIC 3021, Australia
Laura B. Hanson
Department of Cardiology, Alfred Health, Melbourne, VIC 3004, Australia
Jason E. Bloom
Department of Cardiology, Alfred Health, Melbourne, VIC 3004, Australia
Dion Stub
Department of Cardiology, Western Health, Melbourne, VIC 3021, Australia
Angela L. Brennan
Centre of Cardiovascular Research and Education in Therapeutics, Monash University, Melbourne, VIC 3004, Australia
Christopher Reid
Department of Epidemiology and Preventative Medicine, Monash University, Melbourne, VIC 3004, Australia
Diem T. Dinh
Department of Epidemiology and Preventative Medicine, Monash University, Melbourne, VIC 3004, Australia
Jeffrey Lefkovits
Centre of Cardiovascular Research and Education in Therapeutics, Monash University, Melbourne, VIC 3004, Australia
Nicholas Cox
Department of Cardiology, Western Health, Melbourne, VIC 3021, Australia
William Chan
Department of Cardiology, Western Health, Melbourne, VIC 3021, Australia
Background: Patient factors, such as sex and body mass index (BMI), are known to influence patient radiation exposure. Body surface area (BSA) and its association with patient radiation exposure has not been well studied. Methods and Results: We analysed height, weight, BMI and BSA in consecutive patients undergoing cardiac catheterisation and percutaneous coronary intervention (PCI) at a high-volume Australian centre between September 2016 and April 2020 to assess their association with dose–area product (DAP, Gycm2). The mean age of the cohort was 64.5 ± 12.3 years with males comprising 68.8% (n = 8100, 5124 diagnostic cardiac catheterisation cases and 2976 PCI cases). Median male BMI was 28.4 kg/m2 [IQR 25.2–32.1] versus 28.8 kg/m2 [24.7–33.7] for females, p = 0.01. Males had higher BSA (2.0 ± 0.2 m2) than females (1.78 ± 0.2 m2), p = 0.001. Each 0.4 m2 increase in BSA conferred a 1.32x fold change in DAP (95% CI 1.29–1.36, p ≤ 0.001). Each 5 kg/m2 increase in BMI was linked to a 1.13x DAP fold change (1.12–1.14, p ≤ 0.001). Male sex conferred a 1.23x DAP fold change (1.20–1.26, p ≤ 0.001). Multivariable modelling with BMI or BSA explained 14% of DAP variance (R2 0.67 vs. 0.53 for both, p ≤ 0.001). Conclusions: BSA is an important anthropometric measure between the sexes and a key predictor of radiation dose and radiation exposure beyond sex, BMI, and weight.