International Journal of Oral Science (Mar 2025)
Expert consensus on intentional tooth replantation
- Zhengmei Lin,
- Dingming Huang,
- Shuheng Huang,
- Zhi Chen,
- Qing Yu,
- Benxiang Hou,
- Lihong Qiu,
- Wenxia Chen,
- Jiyao Li,
- Xiaoyan Wang,
- Zhengwei Huang,
- Jinhua Yu,
- Jin Zhao,
- Yihuai Pan,
- Shuang Pan,
- Deqin Yang,
- Weidong Niu,
- Qi Zhang,
- Shuli Deng,
- Jingzhi Ma,
- Xiuping Meng,
- Jian Yang,
- Jiayuan Wu,
- Lan Zhang,
- Jin Zhang,
- Xiaoli Xie,
- Jinpu Chu,
- Kehua Que,
- Xuejun Ge,
- Xiaojing Huang,
- Zhe Ma,
- Lin Yue,
- Xuedong Zhou,
- Junqi Ling
Affiliations
- Zhengmei Lin
- Department of Operative Dentistry and Endodontics, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University & Guangdong Provincial Key Laboratory of Stomatology
- Dingming Huang
- State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University
- Shuheng Huang
- Department of Operative Dentistry and Endodontics, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University & Guangdong Provincial Key Laboratory of Stomatology
- Zhi Chen
- State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University
- Qing Yu
- State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shanxi Key Laboratory of Oral Diseases, Department of Operative Dentistry & Endodontics, School of Stomatology, The Fourth Military Medical University
- Benxiang Hou
- Center for Microscope Enhanced Dentistry, Beijing Stomatological Hospital, Capital Medical University
- Lihong Qiu
- Department of Endodontics, School of Stomatology, China Medical University
- Wenxia Chen
- College & Hospital of Stomatology, Guangxi Medical University
- Jiyao Li
- State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University
- Xiaoyan Wang
- Department of Cariology and Endodontology, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology, Peking University
- Zhengwei Huang
- Department of Endodontics, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, National Clinical Research Center for Oral Diseases, National Center for Stomatology, Shanghai Key Laboratory of Stomatology
- Jinhua Yu
- Department of Endodontics, Jiangsu Key Laboratory of Oral Diseases, Affiliated Hospital of Stomatology, Nanjing Medical University
- Jin Zhao
- Department of Endodontics, The First Affiliated Hospital of Xinjiang Medical University
- Yihuai Pan
- Department of Endodontics, School and Hospital of Stomatology, Wenzhou Medical University
- Shuang Pan
- Department of Endodontics, The First Affiliated Hospital of Harbin Medical University & Department of Endodontics, School of Stomatology, Harbin Medical University
- Deqin Yang
- Department of Conservative Dentistry and Endodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University
- Weidong Niu
- School of Stomatology, Dalian Medical University
- Qi Zhang
- Department of Endodontics, Stomatological Hospital and Dental School of Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration
- Shuli Deng
- Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University
- Jingzhi Ma
- Department of Stomatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- Xiuping Meng
- Hospital of Stomatology, Jilin University
- Jian Yang
- Department of Endodontics, The Affiliated Stomatological Hospital of Nanchang University
- Jiayuan Wu
- Key Laboratory of Oral Disease Research, School of Stomatology, Zunyi Medical University
- Lan Zhang
- State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University
- Jin Zhang
- Shandong University, School of Stomatology
- Xiaoli Xie
- Department of Endodontology, Hunan Xiangya Stomatological Hospital, Central South University
- Jinpu Chu
- The First Affiliated Hospital of Zhengzhou University
- Kehua Que
- Department of Endodontics, College of Stomatology, Tianjin Medical University
- Xuejun Ge
- Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology
- Xiaojing Huang
- Fujian Key Laboratory of Oral Disease & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key Lab of Fujian College and University, School and Hospital of Stomatology, Fujian Medical University
- Zhe Ma
- Department of Preventive Dentistry, Hebei Key Laboratory of Stomatology, Hebei Clinical Research Center for Oral Diseases, School and Hospital of Stomatology, Hebei Medical University, Shijiazhuang
- Lin Yue
- Department of Cariology and Endodontology, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology, Peking University
- Xuedong Zhou
- State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University
- Junqi Ling
- Department of Operative Dentistry and Endodontics, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University & Guangdong Provincial Key Laboratory of Stomatology
- DOI
- https://doi.org/10.1038/s41368-024-00337-5
- Journal volume & issue
-
Vol. 17,
no. 1
pp. 1 – 10
Abstract
Abstract Intentional tooth replantation (ITR) is an advanced treatment modality and the procedure of last resort for preserving teeth with inaccessible endodontic or resorptive lesions. ITR is defined as the deliberate extraction of a tooth; evaluation of the root surface, endodontic manipulation, and repair; and placement of the tooth back into its original socket. Case reports, case series, cohort studies, and randomized controlled trials have demonstrated the efficacy of ITR in the retention of natural teeth that are untreatable or difficult to manage with root canal treatment or endodontic microsurgery. However, variations in clinical protocols for ITR exist due to the empirical nature of the original protocols and rapid advancements in the field of oral biology and dental materials. This heterogeneity in protocols may cause confusion among dental practitioners; therefore, guidelines and considerations for ITR should be explicated. This expert consensus discusses the biological foundation of ITR, the available clinical protocols and current status of ITR in treating teeth with refractory apical periodontitis or anatomical aberration, and the main complications of this treatment, aiming to refine the clinical management of ITR in accordance with the progress of basic research and clinical studies; the findings suggest that ITR may become a more consistent evidence-based option in dental treatment.
