Barriers to Creutzfeldt-Jakob Disease Autopsies, California

Abstract

Creutzfeldt-Jakob disease (CJD) surveillance relies on autopsy and neuropathologic evaluation. The 1990–2000 CJD autopsy rate in California was 21%. Most neurologists were comfortable diagnosing CJD (83%), but few pathologists felt comfortable diagnosing CJD (35%) or performing autopsy (29%). Addressing obstacles to autopsy is necessary to improve CJD surveillance.

Keywords

• Creutzfeldt-Jakob Disease
• CJD
• variant
• transmissible spongiform encephalopathy
• TSE
• prion