Nature Communications (Apr 2016)

Fast and sensitive mapping of nanopore sequencing reads with GraphMap

  • Ivan Sović,
  • Mile Šikić,
  • Andreas Wilm,
  • Shannon Nicole Fenlon,
  • Swaine Chen,
  • Niranjan Nagarajan

DOI
https://doi.org/10.1038/ncomms11307
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 11

Abstract

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Read mapping and alignment tools are critical for many applications based on MinION sequencers. Here, the authors present GraphMap, a mapping algorithm designed to analyze nanopore sequencing reads, that progressively refines candidate alignments to handle potentially high error rates to align long reads.