mSystems (Oct 2021)

The Complex Transcriptional Landscape of Magnetosome Gene Clusters in Magnetospirillum gryphiswaldense

  • Marina Dziuba,
  • Cornelius N. Riese,
  • Lion Borgert,
  • Manuel Wittchen,
  • Tobias Busche,
  • Jörn Kalinowski,
  • René Uebe,
  • Dirk Schüler

DOI
https://doi.org/10.1128/mSystems.00893-21
Journal volume & issue
Vol. 6, no. 5

Abstract

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Magnetosomes have emerged as a model system to study prokaryotic organelles and a source of biocompatible magnetic nanoparticles for various biomedical applications. However, the lack of knowledge about the transcriptional organization of magnetosome gene clusters has severely impeded the engineering, manipulation, and transfer of this highly complex biosynthetic pathway into other organisms.