Transfusion-Related acute lung injury in a patient with hellp syndrome: A case report

Abstract

Transfusion-related acute lung injury (TRALI) is a serious adverse reaction associated with the transfusion of plasma-containing blood components, and presents as hypoxemia and non-cardiogenic pulmonary oedema within 6 hrs of transfusion. Here we are reporting a case of TRALI in 24-year-old pregnant Female presented with HELLP (haemolysis, elevated liver enzymes, and low platelet count) syndrome, an emergency caesarean section delivery was performed, and blood was transfused. In such cases, clinicians should strictly monitor the patient's condition at least during the 6 hrs while the patient receives blood transfusion, and should suspect TRALI. The patient's rapid clinical deterioration with falling O2 saturation and other respiratory symptoms after transfusion supports the diagnosis of TRALI.

Keywords

• Acute lung injury
• blood transfusion
• caesarean section
• HELLP syndrome
• transfusion-associated circulatory fluid overload