THE EFFECT OF PENTOXIFYLLINE ON THE PERFORMANCE THE COAGULATION SYSTEM IN PATIENTS WITH THORACOABDOMINAL INJURIES

Abstract

Purpose: to study the effect of pentoxifylline on coagulation system in trauma patients. Materials and methods: conducted a retrospective analysis of 81 medical card of the inpatient with thoracoabdominal trauma. In 26 patients the treatment regimen was included pentoxifylline, 55 patients the drug is not administered. All patients were assessed changes in indicators of the coagulation system. Results: the levels of platelets and APTT in the dynamics decreased, and fibrinogen and PTT increased by the fifth day of treatment. More pronounced these changes were in the group of patients that pentoxifylline was not appointed. The hemoglobin level was more stable in those patients who were administered pentoxifylline. Summary: the inclusion of pentoxifylline in the treatment of patients with thoracoabdominal injuries do not lead to violations of the blood coagulation system.

Keywords

• thoracoabdominal trauma
• pentoxifylline
• coagulation system
• blood loss