CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient

Alexander Plong; Kevin Rodriguez; Mark Alber; Weitao Chen; G. Venugopala Reddy

doi:10.1038/s41467-021-26586-0

Nature Communications (Nov 2021)

CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient

Alexander Plong,
Kevin Rodriguez,
Mark Alber,
Weitao Chen,
G. Venugopala Reddy

Affiliations

Alexander Plong: Department of Botany and Plant Sciences, University of California Riverside
Kevin Rodriguez: Department of Botany and Plant Sciences, University of California Riverside
Mark Alber: Department of Mathematics, University of California Riverside
Weitao Chen: Department of Mathematics, University of California Riverside
G. Venugopala Reddy: Department of Botany and Plant Sciences, University of California Riverside

DOI: https://doi.org/10.1038/s41467-021-26586-0
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 13

Abstract

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WUSCHEL is a critical regulator of stem cell homeostasis at shoot apical meristems. Here the authors show that CLV3 regulates WUSCHEL by not only repressing WUSCHEL transcription but also by controlling nuclear export of WUSCHEL and therefore its diffusion between adjacent cells.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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