Proceedings (Dec 2018)

Integration of Microresonant Sensor into a Microfluidic Platform for the Real Time Analysis of Platelets-Collagen Interaction in Flow Condition

  • Aleksandr Oseev,
  • Benoît Le Roy de Boiseaumarié,
  • Fabien Remy-Martin,
  • Jean-François Manceau,
  • Alain Rouleau,
  • Franck Chollet,
  • Wilfrid Boireau,
  • Thérèse Leblois

DOI
https://doi.org/10.3390/proceedings2130940
Journal volume & issue
Vol. 2, no. 13
p. 940

Abstract

Read online

The contribution focuses on the development of microresonant sensor solution integrated in microfluidic platform for the haemostasis assessment at realistic rheological flow conditions similar to the one in blood vessels. A multi-parameter sensor performs real time analysis of interactions between immobilized collagen and platelets. The detection and characterization of such interactions at controlled flow rates provide information to evaluate the dynamic of each step of primary haemostasis. The microresonant sensor concept was developed and is described in the contribution.

Keywords