Frontiers in Bioengineering and Biotechnology (Apr 2023)

Functional insights to the development of bioactive material for combating bacterial infections

  • Duoyang Fan,
  • Duoyang Fan,
  • Xiaohui Liu,
  • Xiaohui Liu,
  • Yueming Ren,
  • Yueming Ren,
  • Shuaige Bai,
  • Shuaige Bai,
  • Yanbing Li,
  • Ziheng Luo,
  • Ziheng Luo,
  • Jie Dong,
  • Jie Dong,
  • Fei Chen,
  • Fei Chen,
  • Wenbin Zeng,
  • Wenbin Zeng

DOI
https://doi.org/10.3389/fbioe.2023.1186637
Journal volume & issue
Vol. 11

Abstract

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The emergence of antibiotic-resistant “superbugs” poses a serious threat to human health. Nanomaterials and cationic polymers have shown unprecedented advantages as effective antimicrobial therapies due to their flexibility and ability to interact with biological macromolecules. They can incorporate a variety of antimicrobial substances, achieving multifunctional effects without easily developing drug resistance. Herein, this article discusses recent advances in cationic polymers and nano-antibacterial materials, including material options, fabrication techniques, structural characteristics, and activity performance, with a focus on their fundamental active elements.

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