Circadian Clock Control of Translation Initiation Factor eIF2α Activity Requires eIF2γ-Dependent Recruitment of Rhythmic PPP-1 Phosphatase in
<i>Neurospora crassa</i>
Zhaolan Ding,
Teresa M. Lamb,
Ahmad Boukhris,
Rachel Porter,
Deborah Bell-Pedersen
Affiliations
Zhaolan Ding
Department of Biology and Center for Biological Clocks Research, Texas A&M University, College Station, Texas, USA
Teresa M. Lamb
Department of Biology and Center for Biological Clocks Research, Texas A&M University, College Station, Texas, USA
Ahmad Boukhris
Department of Biology and Center for Biological Clocks Research, Texas A&M University, College Station, Texas, USA
Rachel Porter
Department of Biology and Center for Biological Clocks Research, Texas A&M University, College Station, Texas, USA
Deborah Bell-Pedersen
Department of Biology and Center for Biological Clocks Research, Texas A&M University, College Station, Texas, USA
Circadian clock control of mRNA translation contributes to the daily cycling of a significant proportion of the cellular protein synthesis, but how this is accomplished is not understood. We discovered that the clock in the model fungus Neurospora crassa