Structural investigation of methyl 3-(4-fluorobenzoyl)-7-methyl-2-phenylindolizine-1-carboxylate, an inhibitory drug towards Mycobacterium tuberculosis

Abstract

The title compound, C24H18FNO3, crystallizes in the monoclinic centrosymmetric space group P21/n and its molecular conformation is stabilized via C—H...O intramolecular interactions. The supramolecular network mainly comprises C—H...O, C—H...F and C—H...π interactions, which contribute towards the formation of the crystal structure. The different intermolecular interactions have been further analysed via Hirshfeld surface analysis and fingerprint plots.

Keywords

• crystal structure
• anti-tb activity drug
• intermolecular interactions
• hirshfeld surface analysis
• fingerprint plot