Identification of alternative lengthening of telomeres-related genes prognosis model in hepatocellular carcinoma

FanLin Zeng; YuLiang Chen; Jie Lin

doi:10.1186/s12885-024-13146-0

BMC Cancer (Nov 2024)

Identification of alternative lengthening of telomeres-related genes prognosis model in hepatocellular carcinoma

FanLin Zeng,
YuLiang Chen,
Jie Lin

Affiliations

FanLin Zeng: Department of General Surgery (Hepatobiliary and Pancreatic Surgery), The First Affiliated Hospital of Gannan Medical University
YuLiang Chen: Department of Gastroenterology, The First Affiliated Hospital of Gannan Medical University
Jie Lin: Department of Intensive Medicine (Comprehensive Intensive Care Unit), The First Affiliated Hospital of Gannan Medical University

DOI: https://doi.org/10.1186/s12885-024-13146-0
Journal volume & issue: Vol. 24, no. 1
pp. 1 – 18

Abstract

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Highlights 13 ALTDEGs were identified for constructing a risk model model. Risk model and ALTs-score model could be used for HCC prognosis. 13 ALTDEGs could serve as prognostic and diagnostic biomarkers for HCC. SMG5 knockdown suppressed the proliferation, migration, and invasion of HCC cells.

Published in BMC Cancer

ISSN: 1471-2407 (Online)
Publisher: BMC
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: http://bmccancer.biomedcentral.com

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Abstract

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