Patient autoantibodies induce platelet destruction signals via raft-associated glycoprotein Ibα and Fc RIIa in immune thrombocytopenia

• Rolf T. Urbanus,
• Dianne E. van der Wal,
• Cornelis A. Koekman,
• Albert Huisman,
• Dave J. van den Heuvel,
• Hans C. Gerritsen,
• Hans Deckmyn,
• Jan-Willem N. Akkerman,
• Roger E.G. Schutgens,
• Eelo Gitz

Affiliations

Rolf T. Urbanus

Thrombosis and Haemostasis Laboratory, Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, The Netherlands

Dianne E. van der Wal

Thrombosis and Haemostasis Laboratory, Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, The Netherlands

Cornelis A. Koekman

Thrombosis and Haemostasis Laboratory, Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, The Netherlands

Albert Huisman

Thrombosis and Haemostasis Laboratory, Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, The Netherlands

Dave J. van den Heuvel

Department of Molecular Biophysics, Utrecht University, The Netherlands

Hans C. Gerritsen

Department of Molecular Biophysics, Utrecht University, The Netherlands

Hans Deckmyn

Laboratory for Thrombosis Research, KU Leuven, Kortrijk, Belgium

Jan-Willem N. Akkerman

Thrombosis and Haemostasis Laboratory, Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, The Netherlands

Roger E.G. Schutgens

Haematology/Van Creveldkliniek, University Medical Center Utrecht, Utrecht, The Netherlands

Eelo Gitz

Thrombosis and Haemostasis Laboratory, Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, The Netherlands