Nature Communications (Nov 2016)

A multi-marker association method for genome-wide association studies without the need for population structure correction

  • Jonas R. Klasen,
  • Elke Barbez,
  • Lukas Meier,
  • Nicolai Meinshausen,
  • Peter Bühlmann,
  • Maarten Koornneef,
  • Wolfgang Busch,
  • Korbinian Schneeberger

DOI
https://doi.org/10.1038/ncomms13299
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 8

Abstract

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Currently available methods for phenotype to genetic markers association need to account for population structure. Here, Klasen et al. devise a statistical method called Quantitative Trait Cluster Association Test (QTCAT) that overcomes the need for population structure correction.