Communications Biology (Nov 2022)

High-throughput determination of dry mass of single bacterial cells by ultrathin membrane resonators

  • Adrián Sanz-Jiménez,
  • Oscar Malvar,
  • Jose J. Ruz,
  • Sergio García-López,
  • Priscila M. Kosaka,
  • Eduardo Gil-Santos,
  • Álvaro Cano,
  • Dimitris Papanastasiou,
  • Diamantis Kounadis,
  • Jesús Mingorance,
  • Álvaro San Paulo,
  • Montserrat Calleja,
  • Javier Tamayo

DOI
https://doi.org/10.1038/s42003-022-04147-5
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 10

Abstract

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A technological approach combines transport, guiding and focusing of individual bacteria from solution to ultrathin membrane resonators for dry mass determination of single cells with accuracy within 1% and throughput of 20 cells/min.