The influence of lignans on the quality of life of women of perimenopausal age

Abstract

Problems associated with the state of health of women in the second half of her life are one of the priorities of modern medicine. The aim of the study was to determine the efficacy and safety of the drug in comparison with placebo in patients of perimenopausal age. Materials and methods. A randomized study was conducted in 40 patients aged 38 to 55 years without chronic somatic and gynecological diseases. The I group included 20 women who underwent therapy with the test drug (7-hydroxymatairesinol-lignan formula), in the second group - 20 women, placebo-controlled (similar dose of placebo). Conclusion. The results of the study showed that 7-hydroxymatairesinol has an effect on peripheral vasodilation, does not cause side effects (drowsiness, weakness, decreased efficiency, does not lead to fluid retention), improves general condition, causes a decrease in foliculostimulant hormone, has a positive effect on breast tissue, increases sexual activity, affects weight loss, improves carbohydrate and lipid metabolism, as well as intracellular enzymatic activity of the liver.

Keywords

• perimenopause
• phytoestrogens
• tides
• lignans