Robust humoral immune response after boosting in children with Multisystem Inflammatory Syndrome in Children

Abstract

The exact pathogenesis of Multisystem Inflammatory Syndrome in Children (MIS-C) is unknown. Reports on response to vaccination in children who had MIS-C are lacking. Using prospectively enrolled children, we report on humoral immune responses prior to and after SARS-CoV-2 immune rechallenge. Recurrent auricular chondritis was also noted in one child.

Keywords

• Multisystem Inflammatory Syndrome in Children
• Post-vaccination myocarditis
• Auricular chondritis
• Coxsackievirus