Communications Biology (Aug 2022)
Long-term microglial phase-specific dynamics during single vessel occlusion and recanalization
- Xiaoke Xie,
- Xuanting Liu,
- Jiazhu Zhu,
- Yongxian Xu,
- Xiaojing Li,
- Yameng Zheng,
- Shangyue Gong,
- Xiao Xiao,
- Yiwen Chen,
- Jianmin Zhang,
- Wei Gong,
- Ke Si
Affiliations
- Xiaoke Xie
- Department of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine
- Xuanting Liu
- MOE Frontier Science Center for Brain Science & Brain-Machine Integration, NHC and CAMS Key Laboratory of Medical Neurobiology, School of Brain Science and Brain Medicine, Zhejiang University
- Jiazhu Zhu
- State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University
- Yongxian Xu
- MOE Frontier Science Center for Brain Science & Brain-Machine Integration, NHC and CAMS Key Laboratory of Medical Neurobiology, School of Brain Science and Brain Medicine, Zhejiang University
- Xiaojing Li
- MOE Frontier Science Center for Brain Science & Brain-Machine Integration, NHC and CAMS Key Laboratory of Medical Neurobiology, School of Brain Science and Brain Medicine, Zhejiang University
- Yameng Zheng
- MOE Frontier Science Center for Brain Science & Brain-Machine Integration, NHC and CAMS Key Laboratory of Medical Neurobiology, School of Brain Science and Brain Medicine, Zhejiang University
- Shangyue Gong
- Center for Neuroscience and Department of Neurobiology of the Second Affiliated Hospital, State Key laboratory of Modern Optical Instrumentation, Zhejiang University School of Medicine
- Xiao Xiao
- MOE Frontier Science Center for Brain Science & Brain-Machine Integration, NHC and CAMS Key Laboratory of Medical Neurobiology, School of Brain Science and Brain Medicine, Zhejiang University
- Yiwen Chen
- MOE Frontier Science Center for Brain Science & Brain-Machine Integration, NHC and CAMS Key Laboratory of Medical Neurobiology, School of Brain Science and Brain Medicine, Zhejiang University
- Jianmin Zhang
- Center for Neuroscience and Department of Neurobiology of the Second Affiliated Hospital, State Key laboratory of Modern Optical Instrumentation, Zhejiang University School of Medicine
- Wei Gong
- MOE Frontier Science Center for Brain Science & Brain-Machine Integration, NHC and CAMS Key Laboratory of Medical Neurobiology, School of Brain Science and Brain Medicine, Zhejiang University
- Ke Si
- Department of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine
- DOI
- https://doi.org/10.1038/s42003-022-03784-0
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 13
Abstract
The spatiotemporal dynamics of the microglial inflammatory response to single vessel occlusion and recanalization are analysed, revealing four different response phases.
