ANTIBACTERIAL THERAPY OF INFECTIVE ENDOCARDITIS

Abstract

The article analyzes the influence of infective endocarditis etiology on the clinical course of the disease. The role of Staphylococci as common pathogens is emphasized. Streptococci have faded in importance, though, streptococcal endocarditis is still a frequent form of the disease. The authors give the data on bactericidal agents active against the main causative microorganisms in endocarditis; doses, rational combinations and adverse effects are specified. Treatment-requiring common cardiac and extra-cardiac complications of infective endocarditis are also characterized.

Keywords

• infective endocarditis
• treatment
• antibiotics
• bactericidal effect
• penicillins
• aminoglycosides
• streptococcus
• staphylococcus