Negative Histology after Endoscopic Resection: A Pathologist’s Aspect

Abstract

Endoscopic biopsy is the most popular diagnostic procedure for gastric epithelial neoplasm. However, discrepancy between biopsy and endoscopic resection diagnosis occasionally occurs and leads to an unnecessary procedure. A negative pathologic diagnosis following endoscopic resection is particularly problematic. In this context, we reviewed factors that may be associated with a diagnostic discrepancy between endoscopic biopsy and endoscopic resection, with focus on crypt dysplasia.

Keywords

• Biopsy
• Crypt dysplasia
• Endoscopic mucosal resection
• Endoscopic submucosal dissection
• Stomach