Emerging Infectious Diseases (Dec 2009)

Oseltamivir-Resistant Influenza A Pandemic (H1N1) 2009 Virus, Hong Kong, China

  • Honglin Chen,
  • Chung Lam Cheung,
  • Hung Tai,
  • Pengxi Zhao,
  • Jasper F.W. Chan,
  • Vincent C.C. Cheng,
  • Kwok-Hung Chan,
  • K.Y. Yuen

DOI
https://doi.org/10.3201/eid1512.091057
Journal volume & issue
Vol. 15, no. 12
pp. 1970 – 1972

Abstract

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Resistance to oseltamivir was observed in influenza A pandemic (H1N1) 2009 virus isolated from an untreated person in Hong Kong, China. Investigations showed a resistant virus with the neuraminidase (NA) 274Y genotype in quasi-species from a nasopharyngeal aspirate. Monitoring for the naturally occurring NA 274Y mutation in this virus is necessary.

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