Antibiotic profile in pediatric wards, Department of Child Health, Cipto Mangunkusumo Hospital

Abstract

Introduction The medical profession has currently come to a con- clusion that the major problem in the future is failure of treatment due to antibiotic-resistant microorganisms. Objective The aim of this study was to determine the profile of antibiotics used in the Pediatric Wards of Department of Child Health, Medical School, University of Indonesia, Cipto Mangunkusumo Hos- pital, Jakarta. Methods A descriptive retrospective study was conducted on all pa- tients hospitalized in the Pediatric Wards of Department of Child Health, Medical School, University of Indonesia, Cipto Mangunkusumo Hos- pital during June–July 2001. Data were obtained from the medical records of the patients. Results Three hundreds and fifty-six hospitalized patients fulfilled the inclusion criteria. The antibiotics were given to 48.7% of the patients. The greatest user of antibiotics was the age group of 1-5 year-old, 50% of patients had been given single antibiotic and the rest given combined antibiotics. The ICU used antibiotics most fre- quently in contrast to the one-day care unit which used least. The greatest use of single antibiotic was in the class 1-2 wards while combined antibiotics were mostly used in the third class wards. Single antibiotics used were cefotaxime (49.4%), amoxicillin (20.7%), and ampicillin (11.55%). Combined antibiotics used were ampicillin + chloramphenicol (34.5%), cotrimoxazole (21.8%), cefotaxime + amikacin (5.7%), cefotaxime + cotrimoxazole (5.7%), and cefotaxime + isoniazid + rifampicin + pyrazinamide (5.7%). Conclusions The antibiotics most commonly used singly was cefotaxime. The combination of antibiotic mostly used was ampi- cillin + chloramphenicol

Keywords

• antibiotic
• pediatric ward
• hospitalized patients
• single antibiotic
• combined antibiotic