Ketogenic dietary therapy in adult status epilepticus: current progress and clinical application

Abstract

Abstract Status epilepticus (SE) is a common fatal neurological disease with high morbidity and mortality. Even if a large proportion of patients might be relieved from anti-seizure medications, sedatives and anesthetics, some still remain out of control. The ketogenic dietary (KD) has been proven useful in patients refractory to medications and/or who have failed to respond to surgical intervention. Recently, KD has shown beneficial therapeutic effects in children with SE, but studies in adults have rarely been reported. In this paper, we review the efficacy and utility of KD in adult SE patients and highlight its application for clinical reference and management.

Keywords

• Adults
• Drug-resistant epilepsy
• Ketogenic enteral nutrition
• Ketogenic dietary
• Ketogenic parenteral nutrition
• Management