Liver allograft pathology in the late post-transplant period

Abstract

Annually increasing quantity of liver transplants and the growing population of long-survived recipients determine the relevance of late allograft dysfunction study. Variety of morphological and functional disorders of the transplanted liver complicates their timely diagnostics. Moreover, in some patients, serious graft damage may proceed for a long time without clinical manifestations and laboratory abnormalities.The review summarizes the structure, prevalence, risk factors and prognostic value of different liver allograft pathology determined by histological examination in the long term after transplantation.

Keywords

• liver transplantation
• biopsy
• non-alcoholic fatty liver disease
• chronic hepatitis
• idiopathic posttransplantation hepatitis
• graft rejection
• fibrosis
• primary sclerosing cholangitis
• primary biliary cholangitis
• autoimmune hepatitis
• recurrence