Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (Apr 2012)

Strategies for modulating the inflammatory response after decompression from abdominal compartment syndrome

  • Shah Shinil K,
  • Jimenez Fernando,
  • Letourneau Phillip A,
  • Walker Peter A,
  • Moore-Olufemi Stacey D,
  • Stewart Randolph H,
  • Laine Glen A,
  • Cox Charles S

DOI
https://doi.org/10.1186/1757-7241-20-25
Journal volume & issue
Vol. 20, no. 1
p. 25

Abstract

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Abstract Background Management of the open abdomen is an increasingly common part of surgical practice. The purpose of this review is to examine the scientific background for the use of temporary abdominal closure (TAC) in the open abdomen as a way to modulate the local and systemic inflammatory response, with an emphasis on decompression after abdominal compartment syndrome (ACS). Methods A review of the relevant English language literature was conducted. Priority was placed on articles published within the last 5 years. Results/Conclusion Recent data from our group and others have begun to lay the foundation for the concept of TAC as a method to modulate the local and/or systemic inflammatory response in patients with an open abdomen resulting from ACS.

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