Pure transitional cell carcinoma of the ovary presenting as bilateral complex cystic masses in a premenopausal woman – Case report and review of literature

Abstract

The understanding of ovarian malignancy pathogenesis has greatly increased with identification of varied genomic mutation profiles, which directs the clinical behavior of the tumors. The present case describes the rare subtype of pure transitional cell carcinoma which is no more included in the newer World Health Organization (WHO) classification as the WHO labels it as a type of high-grade serous ovarian cancer with transitional cell differentiation, although in our case no serous component was identified. Hence, with revised classification of ovarian malignancies, it is important to report all rare subtypes in order to understand their biology and behavior.

Keywords

• High-grade serous ovarian cancer
• malignant Brenner tumor
• pure transitional cell carcinoma