In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases

Kyle D. Duncan; Xiaofei Sun; Erin S. Baker; Sudhansu K. Dey; Ingela Lanekoff

doi:10.1038/s42003-021-02488-1

Communications Biology (Aug 2021)

In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases

Kyle D. Duncan,
Xiaofei Sun,
Erin S. Baker,
Sudhansu K. Dey,
Ingela Lanekoff

Affiliations

Kyle D. Duncan: Department of Chemistry-BMC, Uppsala University
Xiaofei Sun: College of Medicine, University of Cincinnati
Erin S. Baker: Department of Chemistry, North Carolina State University
Sudhansu K. Dey: College of Medicine, University of Cincinnati
Ingela Lanekoff: Department of Chemistry-BMC, Uppsala University

DOI: https://doi.org/10.1038/s42003-021-02488-1
Journal volume & issue: Vol. 4, no. 1
pp. 1 – 9

Abstract

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Duncan et al. use a mass spectrometry imaging method to assess the localization and concentration of prostaglandins (PGs) in mouse tissues during pregnancy. This study brings new biological insights into the spatial evaluation of PGs in tissues, which could reveal the functional significance of each PGs during different stages of embryo development/pregnancy.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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