iScience (Feb 2024)

Outcomes following the excision of sarcoma and chest wall reconstruction using 3D printed implant

  • Lei Wang,
  • Xiaolong Yan,
  • Jing Li,
  • Jinbo Zhao,
  • Jian Wang,
  • Sanhu Yang,
  • Dichen Li,
  • Changquan Shi,
  • Shaomin Li,
  • Junqi Wang,
  • Tao Jiang,
  • Lijun Huang

Journal volume & issue
Vol. 27, no. 2
p. 108757

Abstract

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Summary: The survival outcomes of patients with chest wall sarcomas (CWS) were evaluated after receiving wide excision and chest wall reconstruction by using three-dimensional printed (3DP) implants. The survival outcomes evaluating the effect of 3DP implants for chest wall reconstruction is lacking. Here, forty-nine patients with CWS underwent radical wide excision and chest wall reconstruction using 3DP implants. The surgical data and long-term survival outcomes were collected and analyzed. With a median follow-up of 36 months, the disease-free survival (DFS) and overall survival (OS) were 31.7% and 58.5%, respectively. In addition, the 3-year DFS and OS can be significantly differentiated using the classification criteria of tumor grade, tumor size tumor area. Hence, wide excision and chest wall reconstruction using three-dimensional printed implants are a safe and effective treatment for chest wall sarcoma. The novel classification criteria of tumor size and area have the potential to predict the prognosis of CWS.

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