The Scientific World Journal (Jan 2002)

Formation of Neural Precursor Cell Populations by Differentiation of Embryonic Stem Cells In Vitro

  • Joy Rathjen,
  • Peter D. Rathjen

DOI
https://doi.org/10.1100/tsw.2002.134
Journal volume & issue
Vol. 2
pp. 690 – 700

Abstract

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Recent interest in the generation of neural lineages by differentiation of embryonic stem cells arises from the opportunities represented by a developmentally normal, unlimited source of material that can be manipulated genetically with precision. Several experimental approaches, which differ conceptually, in the route of differentiation and the characteristics of the resulting cell population have been reported. In this review we undertake a comparative analysis of these approaches and their suitability for experimental investigation or implantation.